WANA (Feb 05) – Iranian researchers have successfully designed a colourimetric nano-biosensor capable of rapidly detecting Parkinson’s disease, offering a potential breakthrough in early diagnosis.

 

Project lead Maryam Nikkhah explained that Parkinson’s is the most common neurodegenerative movement disorder, and currently, there is no effective treatment to slow or stop its progression—only symptom management.

 

Developing systems that can accurately detect Parkinson’s biomarkers in bodily fluids can significantly assist doctors in early diagnosis and disease management.

 

How the Nano-Biosensor Works

Nikkhah described the biosensor as a vial containing gold nanoparticles bonded with specific detection molecules. In the presence of Parkinson’s biomarkers, these nanoparticles aggregate and change colour.

 

– If the markers are present in a patient’s saliva, the solution turns purple.

– If the person is healthy, the solution remains red.

 

This nanosensor-based method enables visual detection of the disease without requiring complex lab equipment.